According to a newly published article, the CBD component of cannabis could help prevent oral infections if it is incorporated in the denture material.
The government-funded study, published last month in Molecules journal, says that bonding CBD with dentures shows “potential to reduce dental biofilms and improve oral health outcomes.”
Researchers incorporated CBD into PMMA, a plastic material that is used to make dentures because of its physical and aesthetic properties. The researchers then evaluated the antimicrobial properties of three different types of bacteria. Staphylococcus aureus, Escherichia coli You can also find out more about the following: Streptococcus galactiae.
The CBD coatings showed “significant bactericidal effect” on Gram-positive bacteria. In terms of Gram-negative bacteria—which are typically more resistant to antibiotics—the CBD coating was ineffective against free-floating, so-called “planktonic” Gram-negative bacteria but effectively eliminated communities of bacteria known as biofilms.
Report: “Biofilm Studies revealed that CBD-infused PMMA reduced biofilms by 99% for Gram-positive as well as Gram-negative bacteria compared to PMMA standard.” CBD interfered with bacterial cell processes, leading to lysis or cell breakdown.
In summary, the authors stated that biofilm studies revealed PMMA/CBD surfaces to be effective in eliminating all pathogens.
This study demonstrated that CBD could be incorporated into dentures to prevent dental biofilms, and reduce dental plaques.
The differences in some cases between CBD-infused PMMA and regular PMMA are striking. Growth of bacteria, for example. S. agalactiae On untreated PMMA, “was 10,000 times higher” than the CBD-treated samples.
The coatings that contain CBD have shown a 95% reduction in cancer. S. aureus You can also find out more about the following: E. coli The biofilm technology and 99.99% decrease in bacterial contamination S. The report states that biofilms are “bio-films”.
The article appeared in Molecules’ special issue dedicated to “intelligent” polymer materials and received funding by the Natural Sciences and Engineering Research Council of Canada.
This investigation provides a novel approach to developing anti-biotic-free coatings. It is an alternative for conventional methods, according to the team of five researchers from Western University (Canada).
The authors note that further research is needed to develop coatings which can release antibiofilm agents over a sustained period of time. This sustained release maintains effective CBD concentrations over an extended time period and maximizes their ability to destroy biofilms.
The study found a “burst” release of CBD in the first 12 hour followed by “a steadily released CBD into the surroundings afterward, in vitro.”
The future should investigate why CBD was not effective in eradicating planktonic bacteria, but it did so successfully with biofilms.
In the article, it is suggested that further investigations could be conducted to understand CBD’s antibiofilm mechanisms. The paper suggests that CBD could also be studied in relation to its effects on biosynthesis of surface proteins and virulence genes.
Separate research has shown that CBD is a potential treatment for common vaginal infections.
The report focused likewise on biofilms and specifically the bacteria Gardnerella vaginalisCBD, found in vaginal bacteria but which can cause vaginosis if out of equilibrium with other microbes. CBD showed antibacterial effects in laboratory testing. G. vaginalis Biofilms should be eliminated.
CBD has antibacterial properties and can reduce biofilms. G. vaginalis This paper stated that “clinical isolates” could be used to treat vaginosis.
In a recent study published in Pharmaceuticals, it was found that CBD can be an effective addition to skin care products because of its anti-aging, antioxidant, and wound healing properties.
This study found that CBD is not only non-toxic to the cells, but also has many other potential properties.
Researchers in India and Thailand published a report last fall that found cannabis oil with CBD could also promote healing skin wounds. They wrote that the product offers “promising” benefits despite the need for better formulations.
This study focused on how cannabis oil could reduce “reactive oxide species” (ROS), during wound healing. These chemicals are “crucial in wound development because they cause cell and tissue injury,” the study explained.
In a paper in Pharmaceutics, the authors stated: “Increased levels of ROS may hinder the healing process by causing inflammation and cellular injury.” CBD’s antioxidant properties reduce these negative effects and create an environment that is more favorable for tissue regeneration.
Another paper, published last July in the Journal of the American Academy of Dermatology, found that applying CBD-infused lotion to the skin appeared to be tied to a lower risk of damage from exposure to ultraviolet (UV) rays. Researchers at George Washington University, Northwestern University, the University of Miami and the Center for Clinical and Cosmetic Research wrote that 21 percent of those who used the CBD cream had less damage than the control group that received a placebo. The damage was similar in another 47 percent, while 11 percent of those who took the CBD lotion showed improved results.
It’s not just for human use.
A separate study, published in the journal Frontiers in Veterinary Science last year, concluded that cannabis appears to be a “viable alternative” treatment option for dogs suffering from a common skin disease—especially if they experience adverse side effects from conventional steroid therapies
This study examined the effectiveness of CBD full spectrum oil in treating a dog suffering from discoid Lupus Erythematosus. This condition causes redness and hair loss that may progress into lesions. It is usually treated by corticosteroids or other drugs that put strain on the liver.
A veterinarian prescribed a full-spectrum oil with a 2:1 THC:CBD ratio, which was administered orally—at first, one drop per day for three days and gradually increasing it “until the optimal dose for symptom control was identified.”
According to the study, “Within weeks, the canine showed significant improvements on the skin, as well as an improvement of liver function.” It is interesting to note that the owner noticed a change in her dog’s behaviour shortly after stopping prednisolone, and on the day she received the cannabis oil.
A study published earlier this year found that over 1/10 of Americans consumed the non-psychoactive component of cannabis within the last month. The prevalence was significantly higher for people who used marijuana.
According to a poll, 7 in 10 marijuana consumers plan to spend more or the same amount on cannabis by 2025.
Kimzy Nanney is the photographer.